Function and Biology Details
Reaction catalysed:
Adenine in double-stranded RNA + H(2)O = hypoxanthine in double-stranded RNA + NH(3)
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Double-stranded RNA-specific adenosine deaminase (preferred)
PDBe Complex ID:
PDB-CPX-157286 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Double-stranded RNA-specific adenosine deaminase
Molecule details ›
Chain: A
Length: 77 amino acids
Theoretical weight: 8.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Adenosine deaminase z-alpha domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Length: 77 amino acids
Theoretical weight: 8.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P55265 (Residues: 125-201; Coverage: 6%)
Sequence domains: Adenosine deaminase z-alpha domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
molecular dynamics
Expression system: Escherichia coli
