› 1qqs

X-ray diffraction
2.4Å resolution

NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN HOMODIMER

Released:
DOI: 10.2210/pdb1qqs/pdb
PDB entry 1qqs coloured by chain, front view.
PDB entry 1qqs coloured by chain, side view.
PDB entry 1qqs coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Ligand preference inferred from the structure of neutrophil gelatinase associated lipocalin.
Goetz DH, Willie ST, Armen RS, Bratt T, Borregaard N, Strong RK
Biochemistry 39 1935-41 (2000)
PMID: 10684642

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160358 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Neutrophil gelatinase-associated lipocalin Chain: A
Molecule details ›
Chain: A
Length: 174 amino acids
Theoretical weight: 20.01 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
UniProt:
  • Canonical: P80188 (Residues: 24-197; Coverage: 98%)
Gene names: HNL, LCN2, NGAL
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
1 bound ligand:
Ligand DKA 1 x DKA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P41212
Unit cell:
a: 54.29Å b: 54.29Å c: 121.98Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.219 0.287
Expression system: unidentified baculovirus

Quick links

Citations

32 review citations

Enterobactin: an archetype for microbial iron transport.
Raymond et al. (2003)
31 more

6 mentions without citation

Redox-regulated chaperones.
Kumsta et al. (2009)
5 more