› 1qqw

X-ray diffraction
2.75Å resolution

CRYSTAL STRUCTURE OF HUMAN ERYTHROCYTE CATALASE

Released:
DOI: 10.2210/pdb1qqw/pdb
PDB entry 1qqw coloured by chain, front view.
PDB entry 1qqw coloured by chain, side view.
PDB entry 1qqw coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure of human erythrocyte catalase.
Ko TP, Safo MK, Musayev FN, Di Salvo ML, Wang C, Wu SH, Abraham DJ
Acta Crystallogr D Biol Crystallogr 56 241-5 (2000)
PMID: 10666617

Function and Biology Details

Reaction catalysed: 
2 H(2)O(2) = O(2) + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137332 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Catalase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 527 amino acids
Theoretical weight: 59.84 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P04040 (Residues: 1-527; Coverage: 100%)
Gene name: CAT
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand HEM 4 x HEM
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 84.904Å b: 141.674Å c: 232.46Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.263 0.206 0.272

Quick links

Citations

3 review citations

Role of Catalase in Oxidative Stress- and Age-Associated Degenerative Diseases.
Nandi et al. (2019)
2 more

17 mentions without citation

Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins.
Huang et al. (2018)
16 more