› 1rw2

Solution NMR

Three-dimensional structure of Ku80 CTD

Released:
DOI: 10.2210/pdb1rw2/pdb
PDB entry 1rw2 coloured by chain, ensemble of 10 models, front view.
PDB entry 1rw2 coloured by chain, ensemble of 10 models, side view.
PDB entry 1rw2 coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the C-terminal domain of Ku80 suggests important sites for protein-protein interactions.
Zhang Z, Hu W, Cano L, Lee TD, Chen DJ, Chen Y
Structure 12 495-502 (2004)
PMID: 15016365

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146431 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
X-ray repair cross-complementing protein 5 Chain: A
Molecule details ›
Chain: A
Length: 152 amino acids
Theoretical weight: 17.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P13010 (Residues: 566-710; Coverage: 20%)
Gene names: G22P2, XRCC5
Sequence domains: Ku C terminal domain like
Structure domains: Ku, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

10 review citations

Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining.
Mahaney et al. (2009)
9 more

4 mentions without citation

Repair of double-strand breaks by end joining.
Chiruvella et al. (2013)
3 more