› 1ry6

X-ray diffraction
1.6Å resolution

Crystal Structure of Internal Kinesin Motor Domain

Released:
DOI: 10.2210/pdb1ry6/pdb
PDB entry 1ry6 coloured by chain, front view.
PDB entry 1ry6 coloured by chain, side view.
PDB entry 1ry6 coloured by chain, top view.
Source organism: Plasmodium falciparum
Primary publication:
Structure of a kinesin microtubule depolymerization machine.
Shipley K, Hekmat-Nejad M, Turner J, Moores C, Anderson R, Milligan R, Sakowicz R, Fletterick R
EMBO J 23 1422-32 (2004)
PMID: 15029249

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184681 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin motor domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 360 amino acids
Theoretical weight: 40.76 KDa
Source organism: Plasmodium falciparum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8I4Y0 (Residues: 43-371; Coverage: 25%)
Gene name: PF3D7_1245100
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P3221
Unit cell:
a: 105.588Å b: 105.588Å c: 84.771Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.207 0.205 0.231
Expression system: Escherichia coli

Quick links

Citations

18 review citations

Intracellular transport and kinesin superfamily proteins, KIFs: structure, function, and dynamics.
Hirokawa et al. (2008)
17 more

7 mentions without citation

Probing the local dynamics of nucleotide-binding pocket coupled to the global dynamics: myosin versus kinesin.
Zheng et al. (2005)
6 more