› 1s3a

Solution NMR

NMR Solution Structure of Subunit B8 from Human NADH-Ubiquinone Oxidoreductase Complex I (CI-B8)

Released:
DOI: 10.2210/pdb1s3a/pdb
PDB entry 1s3a coloured by chain, ensemble of 19 models, front view.
PDB entry 1s3a coloured by chain, ensemble of 19 models, side view.
PDB entry 1s3a coloured by chain, ensemble of 19 models, top view.
Source organism: Homo sapiens
Primary publication:
The oxidized subunit B8 from human complex I adopts a thioredoxin fold.
Brockmann C, Diehl A, Rehbein K, Strauss H, Schmieder P, Korn B, Kühne R, Oschkinat H
Structure 12 1645-54 (2004)
PMID: 15341729

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129060 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 Chain: A
Molecule details ›
Chain: A
Length: 102 amino acids
Theoretical weight: 11.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O43678 (Residues: 1-99; Coverage: 100%)
Gene name: NDUFA2
Sequence domains: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated anealing
Expression system: Escherichia coli BL21

Quick links

Citations

7 review citations

Energy converting NADH:quinone oxidoreductase (complex I).
Brandt U. (2006)
6 more

4 mentions without citation

The Mysterious Multitude: Structural Perspective on the Accessory Subunits of Respiratory Complex I.
Padavannil et al. (2021)
3 more