Function and Biology Details
Reaction catalysed:
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140139 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Activin receptor type-2B
Molecule details ›
Chains: A, C
Length: 98 amino acids
Theoretical weight: 11.57 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: Activin types I and II receptor domain
Structure domains: CD59
Length: 98 amino acids
Theoretical weight: 11.57 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
P27040 (Residues: 23-120; Coverage: 19%)
Sequence domains: Activin types I and II receptor domain
Structure domains: CD59
Inhibin beta A chain
Molecule details ›
Chains: B, D
Length: 116 amino acids
Theoretical weight: 12.99 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Length: 116 amino acids
Theoretical weight: 12.99 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical: P08476 (Residues: 311-426; Coverage: 29%)
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 8.2.2
Spacegroup:
P21212
Expression systems:
- Escherichia coli
- Cricetulus griseus
