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Infrared spectroscopy

Conformational Mapping of Mini-B: An N-terminal/C-terminal Construct of Surfactant Protein B Using 13C-Enhanced Fourier Transform Infrared (FTIR) Spectroscopy

Released:
DOI: 10.2210/pdb1ssz/pdb
PDB entry 1ssz coloured by chain, ensemble of 10 models, front view.
PDB entry 1ssz coloured by chain, ensemble of 10 models, side view.
PDB entry 1ssz coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
The role of charged amphipathic helices in the structure and function of surfactant protein B.
Waring AJ, Walther FJ, Gordon LM, Hernandez-Juviel JM, Hong T, Sherman MA, Alonso C, Alig T, Braun A, Bacon D, Zasadzinski JA
J Pept Res 66 364-74 (2005)
PMID: 16316452

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139872 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pulmonary surfactant-associated protein B Chain: A
Molecule details ›
Chain: A
Length: 34 amino acids
Theoretical weight: 3.93 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P07988 (Residues: 208-278; Coverage: 10%)
Gene names: SFTP3, SFTPB

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Expression system: Not provided

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Citations

11 review citations

Biochemical and pharmacological differences between preparations of exogenous natural surfactant used to treat Respiratory Distress Syndrome: role of the different components in an efficient pulmonary surfactant.
Blanco et al. (2007)
10 more

7 mentions without citation

Critical structural and functional roles for the N-terminal insertion sequence in surfactant protein B analogs.
Walther et al. (2010)
6 more