Function and Biology Details
Reactions catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153641 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Breast cancer type 1 susceptibility protein
Molecule details ›
Chain: A
Length: 214 amino acids
Theoretical weight: 24.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: BRCA1 C Terminus (BRCT) domain
Structure domains: BRCT domain
Length: 214 amino acids
Theoretical weight: 24.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P38398 (Residues: 1646-1859; Coverage: 12%)
Sequence domains: BRCA1 C Terminus (BRCT) domain
Structure domains: BRCT domain
Fanconi anemia group J protein
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 962 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 8 amino acids
Theoretical weight: 962 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: Q9BX63 (Residues: 988-995; Coverage: 1%)
