› 1t5q

Solution NMR

Solution Structure of GIP(1-30)amide in TFE/Water

Released:
DOI: 10.2210/pdb1t5q/pdb
PDB entry 1t5q coloured by chain, ensemble of 20 models, front view.
PDB entry 1t5q coloured by chain, ensemble of 20 models, side view.
PDB entry 1t5q coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide.
Alaña I, Hewage CM, Malthouse JP, Parker JC, Gault VA, O'Harte FP
Biochem Biophys Res Commun 325 281-6 (2004)
PMID: 15522230

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140730 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gastric inhibitory polypeptide Chain: A
Molecule details ›
Chain: A
Length: 30 amino acids
Theoretical weight: 3.54 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P09681 (Residues: 52-81; Coverage: 23%)
Gene name: GIP
Sequence domains: Peptide hormone

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: TORSION ANGLE DYNAMICS, SIMULATED ANNEALING, CONJUGATE-GRADIENT MINIMISATION, POWELL MINIMISATION
Expression system: Not provided

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Citations

1 review citation

Structural aspects of gut peptides with therapeutic potential for type 2 diabetes.
Hewage et al. (2013)
11 other articles