› 1t6f

X-ray diffraction
1.47Å resolution

Crystal Structure of the Coiled-coil Dimerization Motif of Geminin

Released:
DOI: 10.2210/pdb1t6f/pdb
PDB entry 1t6f coloured by chain, front view.
PDB entry 1t6f coloured by chain, side view.
PDB entry 1t6f coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the coiled-coil dimerization motif of geminin: structural and functional insights on DNA replication regulation.
Thépaut M, Maiorano D, Guichou JF, Augé MT, Dumas C, Méchali M, Padilla A
J Mol Biol 342 275-87 (2004)
PMID: 15313623

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130998 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Geminin Chains: A, B
Molecule details ›
Chains: A, B
Length: 37 amino acids
Theoretical weight: 4.4 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O75496 (Residues: 109-145; Coverage: 18%)
Gene name: GMNN

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 25.12Å b: 43.44Å c: 67.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.179 0.221
Expression system: Not provided

Quick links

Citations

2 review citations

Preventing re-replication of chromosomal DNA.
Blow et al. (2005)
1 more

5 mentions without citation

Tetrameric Ctp1 coordinates DNA binding and DNA bridging in DNA double-strand-break repair.
Andres et al. (2015)
4 more