Function and Biology Details
Reaction catalysed:
Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
alpha-thrombin complex and Antithrombin-III (preferred)
PDBe Complex ID:
PDB-CPX-133063 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (7 distinct):
Ligands and Environments
No modified residues
Experiments and Validation Details
X-ray source:
SRS BEAMLINE PX14.1
Spacegroup:
P212121
Expression system: Cricetulus griseus