› 1tfi

Solution NMR

A NOVEL ZN FINGER MOTIF IN THE BASAL TRANSCRIPTIONAL MACHINERY: THREE-DIMENSIONAL NMR STUDIES OF THE NUCLEIC-ACID BINDING DOMAIN OF TRANSCRIPTIONAL ELONGATION FACTOR TFIIS

Released:
DOI: 10.2210/pdb1tfi/pdb
PDB entry 1tfi coloured by chain, ensemble of 12 models, front view.
PDB entry 1tfi coloured by chain, ensemble of 12 models, side view.
PDB entry 1tfi coloured by chain, ensemble of 12 models, top view.
Source organism: Homo sapiens
Primary publication:
Novel zinc finger motif in the basal transcriptional machinery: three-dimensional NMR studies of the nucleic acid binding domain of transcriptional elongation factor TFIIS.
Qian X, Gozani SN, Yoon H, Jeon CJ, Agarwal K, Weiss MA
Biochemistry 32 9944-59 (1993)
PMID: 8399164

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149891 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription elongation factor A protein 1 Chain: A
Molecule details ›
Chain: A
Length: 50 amino acids
Theoretical weight: 5.67 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P23193 (Residues: 252-301; Coverage: 17%)
Gene names: GTF2S, TCEA1, TFIIS
Sequence domains: Transcription factor S-II (TFIIS)
Structure domains: N-terminal domain of TfIIb

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

9 review citations

DNA primases.
Frick et al. (2001)
8 more

23 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
22 more