Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134272 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Lymphotoxin-alpha
Molecule details ›
Chain: A
Length: 144 amino acids
Theoretical weight: 15.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls
Length: 144 amino acids
Theoretical weight: 15.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P01374 (Residues: 62-205; Coverage: 84%)
Sequence domains: TNF(Tumour Necrosis Factor) family
Structure domains: Jelly Rolls
Tumor necrosis factor-binding protein 1
Molecule details ›
Chain: R
Length: 139 amino acids
Theoretical weight: 15.77 KDa
Source organism: Homo sapiens
Expression system: SF9 cells
UniProt:
Sequence domains: TNFR/NGFR cysteine-rich region
Structure domains: Tumor Necrosis Factor Receptor, subunit A, domain 2
Length: 139 amino acids
Theoretical weight: 15.77 KDa
Source organism: Homo sapiens
Expression system: SF9 cells
UniProt:
- Canonical: P19438 (Residues: 44-182; Coverage: 33%)
Sequence domains: TNFR/NGFR cysteine-rich region
Structure domains: Tumor Necrosis Factor Receptor, subunit A, domain 2
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Spacegroup:
I23
Expression systems:
- Escherichia coli
- SF9 cells
