› 1tr4

Solution NMR

Solution structure of human oncogenic protein gankyrin

Released:
DOI: 10.2210/pdb1tr4/pdb
PDB entry 1tr4 coloured by chain, ensemble of 20 models, front view.
PDB entry 1tr4 coloured by chain, ensemble of 20 models, side view.
PDB entry 1tr4 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure--function relationship.
Yuan C, Li J, Mahajan A, Poi MJ, Byeon IJ, Tsai MD
Biochemistry 43 12152-61 (2004)
PMID: 15379554

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131139 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
26S proteasome non-ATPase regulatory subunit 10 Chain: A
Molecule details ›
Chain: A
Length: 226 amino acids
Theoretical weight: 24.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75832 (Residues: 1-226; Coverage: 100%)
Gene name: PSMD10
Sequence domains: Ankyrin repeats (3 copies)
Structure domains: Ankyrin repeat-containing domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Structure-function analysis of TRPV channels.
Niemeyer BA. (2005)
4 more

5 mentions without citation

A primer on ankyrin repeat function in TRP channels and beyond.
Gaudet R. (2008)
4 more