› 1tuz

Solution NMR

NMR Structure of the Diacylglycerol kinase alpha, NESGC target HR532

Released:
DOI: 10.2210/pdb1tuz/pdb
PDB entry 1tuz coloured by chain, ensemble of 20 models, front view.
PDB entry 1tuz coloured by chain, ensemble of 20 models, side view.
PDB entry 1tuz coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Liu G, Shao Y, Xiao R, Acton T, Montelione GT, Szyperski T, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Reactions catalysed: 
ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate
ATP + 1-O-alkyl-sn-glycerol = ADP + 1-O-alkyl-sn-glycerol 3-phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150056 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Diacylglycerol kinase alpha Chain: A
Molecule details ›
Chain: A
Length: 118 amino acids
Theoretical weight: 13.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P23743 (Residues: 1-118; Coverage: 16%)
Gene names: DAGK, DAGK1, DGKA
Sequence domains: Diacylglycerol kinase N-terminus
Structure domains: Diacylglycerol kinase alpha.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry simulated annealing torsion angle dynamics
Expression system: Escherichia coli

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