› 1u19

X-ray diffraction
2.2Å resolution

Crystal Structure of Bovine Rhodopsin at 2.2 Angstroms Resolution

Released:
DOI: 10.2210/pdb1u19/pdb
PDB entry 1u19 coloured by chain, front view.
PDB entry 1u19 coloured by chain, side view.
PDB entry 1u19 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure.
Okada T, Sugihara M, Bondar AN, Elstner M, Entel P, Buss V
J Mol Biol 342 571-83 (2004)
PMID: 15327956

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136065 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Rhodopsin Chains: A, B
Molecule details ›
Chains: A, B
Length: 349 amino acids
Theoretical weight: 39.06 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02699 (Residues: 1-348; Coverage: 100%)
Gene name: RHO
Sequence domains:
Structure domains: Rhodopsin 7-helix transmembrane proteins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
6 bound ligands:
Ligand HG 6 x HG
Ligand ZN 7 x ZN
Ligand RET 2 x RET
Ligand PLM 6 x PLM
Ligand HTG 4 x HTG
Ligand HTO 1 x HTO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU
Spacegroup: P41
Unit cell:
a: 96.68Å b: 96.68Å c: 150.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.2 0.222

Quick links

Citations

74 review citations

The structure and function of G-protein-coupled receptors.
Rosenbaum et al. (2009)
73 more

491 mentions without citation

Structure-function of the G protein-coupled receptor superfamily.
Katritch et al. (2013)
490 more