› 1u9a

X-ray diffraction
2Å resolution

HUMAN UBIQUITIN-CONJUGATING ENZYME UBC9

Released:
DOI: 10.2210/pdb1u9a/pdb
PDB entry 1u9a coloured by chain, front view.
PDB entry 1u9a coloured by chain, side view.
PDB entry 1u9a coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crystal structure of murine/human Ubc9 provides insight into the variability of the ubiquitin-conjugating system.
Tong H, Hateboer G, Perrakis A, Bernards R, Sixma TK
J Biol Chem 272 21381-7 (1997)
PMID: 9261152

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159077 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SUMO-conjugating enzyme UBC9 Chain: A
Molecule details ›
Chain: A
Length: 160 amino acids
Theoretical weight: 18.26 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P63280 (Residues: 1-158; Coverage: 100%)
Gene names: Ubc9, Ubce2i, Ubce9, Ube2i
Sequence domains: Ubiquitin-conjugating enzyme
Structure domains: Ubiquitin Conjugating Enzyme

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: P21
Unit cell:
a: 52.04Å b: 35.18Å c: 58.1Å
α: 90° β: 111.2° γ: 90°
R-values:
R R work R free
0.16 0.16 0.25
Expression system: Escherichia coli

Quick links

Citations

17 review citations

The ubiquitin system.
Hershko et al. (1998)
16 more

11 mentions without citation

Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation.
Knipscheer et al. (2007)
10 more