› 1uky

X-ray diffraction
2.13Å resolution

SUBSTRATE SPECIFICITY AND ASSEMBLY OF CATALYTIC CENTER DERIVED FROM TWO STRUCTURES OF LIGATED URIDYLATE KINASE

Released:
DOI: 10.2210/pdb1uky/pdb
PDB entry 1uky coloured by chain, front view.
PDB entry 1uky coloured by chain, side view.
PDB entry 1uky coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Substrate specificity and assembly of the catalytic center derived from two structures of ligated uridylate kinase.
M��ller-Dieckmann HJ, Schulz GE
J. Mol. Biol. 246 522-30 (1995)
PMID: 7877173

Function and Biology Details

Reaction catalysed: 
ATP + (d)CMP = ADP + (d)CDP
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147467 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uridylate kinase Chain: A
Molecule details ›
Chain: A
Length: 203 amino acids
Theoretical weight: 22.83 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Not provided
UniProt:
  • Canonical: P15700 (Residues: 2-204; Coverage: 100%)
Gene names: SOC8, URA6, YKL024C
Sequence domains: Adenylate kinase
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:
Ligand ADP 2 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P6122
Unit cell:
a: 64.2Å b: 64.2Å c: 185Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.178 not available
Expression system: Not provided

Quick links

Citations

2 review citations

Structural dynamics of bio-macromolecules by NMR: the slowly relaxing local structure approach.
Meirovitch et al. (2010)
1 more

4 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
3 more