› 1v49

Solution NMR

Solution structure of microtubule-associated protein light chain-3

Released:
DOI: 10.2210/pdb1v49/pdb
PDB entry 1v49 coloured by chain, front view.
PDB entry 1v49 coloured by chain, side view.
PDB entry 1v49 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of microtubule-associated protein light chain 3 and identification of its functional subdomains.
Kouno T, Mizuguchi M, Tanida I, Ueno T, Kanematsu T, Mori Y, Shinoda H, Hirata M, Kominami E, Kawano K
J Biol Chem 280 24610-7 (2005)
PMID: 15857831

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190445 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Microtubule-associated proteins 1A/1B light chain 3B Chain: A
Molecule details ›
Chain: A
Length: 120 amino acids
Theoretical weight: 14.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9GZQ8 (Residues: 1-120; Coverage: 96%)
Gene names: MAP1ALC3, MAP1LC3B
Sequence domains: Autophagy protein Atg8 ubiquitin like
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing
Expression system: Escherichia coli

Quick links

Citations

13 review citations

Microtubules and their role in cellular stress in cancer.
Parker et al. (2014)
12 more

12 mentions without citation

Atg8: an autophagy-related ubiquitin-like protein family.
Shpilka et al. (2011)
11 more