› 1va3

Solution NMR

Solution Structure of Transcription Factor Sp1 DNA Binding Domain (Zinc Finger 3)

Released:
DOI: 10.2210/pdb1va3/pdb
PDB entry 1va3 coloured by chain, ensemble of 31 models, front view.
PDB entry 1va3 coloured by chain, ensemble of 31 models, side view.
PDB entry 1va3 coloured by chain, ensemble of 31 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR structure of transcription factor Sp1 DNA binding domain.
Oka S, Shiraishi Y, Yoshida T, Ohkubo T, Sugiura Y, Kobayashi Y
Biochemistry 43 16027-35 (2004)
PMID: 15609997

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139897 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription factor Sp1 Chain: A
Molecule details ›
Chain: A
Length: 29 amino acids
Theoretical weight: 3.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P08047 (Residues: 684-712; Coverage: 4%)
Gene names: SP1, TSFP1
Sequence domains: Zinc finger, C2H2 type

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Escherichia coli

Quick links

Citations

13 review citations

Sp transcription factor family and its role in cancer.
Safe et al. (2005)
12 more

3 mentions without citation

Regulation of cellular senescence by eukaryotic members of the FAH superfamily - A role in calcium homeostasis?
Weiss et al. (2020)
2 more