› 1vca

X-ray diffraction
1.8Å resolution

CRYSTAL STRUCTURE OF AN INTEGRIN-BINDING FRAGMENT OF VASCULAR CELL ADHESION MOLECULE-1 AT 1.8 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1vca/pdb
PDB entry 1vca coloured by chain, front view.
PDB entry 1vca coloured by chain, side view.
PDB entry 1vca coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution.
Jones EY, Harlos K, Bottomley MJ, Robinson RC, Driscoll PC, Edwards RM, Clements JM, Dudgeon TJ, Stuart DI
Nature 373 539-44 (1995)
PMID: 7531291

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148551 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Soluble Vascular Cell Adhesion Molecule-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 202 amino acids
Theoretical weight: 22.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P19320 (Residues: 25-226; Coverage: 28%)
Gene name: VCAM1
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P212121
Unit cell:
a: 52.7Å b: 66.5Å c: 113.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.202 not available
Expression system: Escherichia coli

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Citations

36 review citations

RNA virus mutations and fitness for survival.
Domingo et al. (1997)
35 more

18 mentions without citation

Discrete-continuous duality of protein structure space.
Sadreyev et al. (2009)
17 more