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Solution NMR

Solution Structure Of The DNA Complex Of Human Trf2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-114721 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Telomeric repeat-binding factor 2 Chain: A
Molecule details ›
Chain: A
Length: 63 amino acids
Theoretical weight: 7.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15554 (Residues: 480-542; Coverage: 12%)
Gene names: TERF2, TRBF2, TRF2
Sequence domains: Myb-like DNA-binding domain
Structure domains: Homeodomain-like
Short G-rich strand Chain: B
Molecule details ›
Chain: B
Length: 13 nucleotides
Theoretical weight: 4.1 KDa
Source organism: Homo sapiens
Expression system: Not provided
Short C-rich starnd Chain: C
Molecule details ›
Chain: C
Length: 13 nucleotides
Theoretical weight: 3.84 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing
Expression systems:
  • Escherichia coli
  • Not provided