› 1w0s

X-ray solution scattering

Solution structure of trimeric form of properdin by X-ray solution scattering and analytical ultracentrifugation

Released:
DOI: 10.2210/pdb1w0s/pdb
PDB entry 1w0s coloured by chain, front view.
PDB entry 1w0s coloured by chain, side view.
PDB entry 1w0s coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The dimeric and trimeric solution structures of the multidomain complement protein properdin by X-ray scattering, analytical ultracentrifugation and constrained modelling.
Sun Z, Reid KB, Perkins SJ
J Mol Biol 343 1327-43 (2004)
PMID: 15491616

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151102 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Properdin Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 442 amino acids
Theoretical weight: 48.55 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P27918 (Residues: 28-469; Coverage: 100%)
Gene names: CFP, PFC
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

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Citations

11 review citations

X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution.
Putnam et al. (2007)
10 more

3 mentions without citation

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo.
Chen et al. (2017)
2 more