Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138315 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin-like growth factor-binding protein 4
Molecule details ›
Chain: B
Length: 80 amino acids
Theoretical weight: 8.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Insulin-like growth factor binding protein
Structure domains: Omega-AgatoxinV
Length: 80 amino acids
Theoretical weight: 8.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P22692 (Residues: 24-103; Coverage: 34%)
Sequence domains: Insulin-like growth factor binding protein
Structure domains: Omega-AgatoxinV
Insulin-like growth factor I
Molecule details ›
Chain: I
Length: 70 amino acids
Theoretical weight: 7.66 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Sequence domains: Insulin/IGF/Relaxin family
Structure domains: Insulin-like
Length: 70 amino acids
Theoretical weight: 7.66 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P05019 (Residues: 49-118; Coverage: 40%)
Sequence domains: Insulin/IGF/Relaxin family
Structure domains: Insulin-like
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
MPG/DESY, HAMBURG BEAMLINE BW6
Spacegroup:
P212121
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
