› 1wso

Solution NMR

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-129028 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Orexin-A Chain: A
Molecule details ›
Chain: A
Length: 34 amino acids
Theoretical weight: 3.57 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O43612 (Residues: 34-66; Coverage: 34%)
Gene names: HCRT, OX, PPORX, PPOX

Ligands and Environments

No bound ligands
1 modified residue:
Ligand PCA 1 x PCA

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing torsion angle dynamics
Expression system: Not provided

Quick links

Citations

4 review citations

Orexin neuronal circuitry: role in the regulation of sleep and wakefulness.
Ohno et al. (2008)
3 more

4 mentions without citation

Toward an understanding of agonist binding to human Orexin-1 and Orexin-2 receptors with G-protein-coupled receptor modeling and site-directed mutagenesis.
Heifetz et al. (2013)
3 more