› 1wvn

X-ray diffraction
2.1Å resolution

Crystal Structure of domain 3 of human alpha polyC binding protein

Released:
DOI: 10.2210/pdb1wvn/pdb
PDB entry 1wvn coloured by chain, front view.
PDB entry 1wvn coloured by chain, side view.
PDB entry 1wvn coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structure and RNA binding of the third KH domain of poly(C)-binding protein 1.
Sidiqi M, Wilce JA, Vivian JP, Porter CJ, Barker A, Leedman PJ, Wilce MC
Nucleic Acids Res 33 1213-21 (2005)
PMID: 15731341

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172261 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Poly(rC)-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 82 amino acids
Theoretical weight: 8.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15365 (Residues: 278-356; Coverage: 22%)
Gene name: PCBP1
Sequence domains: KH domain
Structure domains: K Homology domain, type 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21212
Unit cell:
a: 33.4Å b: 71Å c: 29.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.19 0.248
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Heterogeneous nuclear ribonucleoproteins (hnRNPs) in cellular processes: Focus on hnRNP E1's multifunctional regulatory roles.
Chaudhury et al. (2010)
3 more

15 mentions without citation

Management versus miscues in the cytosolic labile iron pool: The varied functions of iron chaperones.
Philpott et al. (2020)
14 more