› 1wyr

Solution NMR

Solution structure of the CH domain of human Rho guanine nucleotide exchange factor 6

Released:
DOI: 10.2210/pdb1wyr/pdb
PDB entry 1wyr coloured by chain, ensemble of 20 models, front view.
PDB entry 1wyr coloured by chain, ensemble of 20 models, side view.
PDB entry 1wyr coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Tomizawa T, Kigawa T, Koshiba S, Inoue M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172175 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho guanine nucleotide exchange factor 6 Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 12.95 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q15052 (Residues: 4-111; Coverage: 14%)
Gene names: ARHGEF6, COOL2, KIAA0006, PIXA
Sequence domains: Calponin homology (CH) domain
Structure domains: Calponin-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, restrainted molecular dynamics
Expression system: Not provided

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