› 1x3s

X-ray diffraction
1.32Å resolution

Crystal structure of human Rab18 in complex with Gppnhp

Released:
DOI: 10.2210/pdb1x3s/pdb
PDB entry 1x3s coloured by chain, front view.
PDB entry 1x3s coloured by chain, side view.
PDB entry 1x3s coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Kukimoto-Niino M, Murayama K, Chen L, Liu ZJ, Wang BC, Shirouzu M, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192459 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-18 Chain: A
Molecule details ›
Chain: A
Length: 195 amino acids
Theoretical weight: 21.76 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9NP72 (Residues: 1-182; Coverage: 88%)
Gene name: RAB18
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand GNP 1 x GNP
1 modified residue:
Ligand MSE 3 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 37.889Å b: 65.182Å c: 40.71Å
α: 90° β: 91.42° γ: 90°
R-values:
R R work R free
0.185 0.185 0.21
Expression system: Not provided

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