Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Ras guanine-nucleotide exchange factors catalytic domain
- Ras-like guanine nucleotide exchange factor, N-terminal
- Dbl homology (DH) domain
- Pleckstrin homology domain
- Dbl homology (DH) domain superfamily
- Ras guanine-nucleotide exchange factor, conserved site
- Ras guanine-nucleotide exchange factor, catalytic domain superfamily
- Ras guanine nucleotide exchange factor domain superfamily
2 more domains
Structure domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Son of sevenless homolog 1 (preferred)
PDBe Complex ID:
PDB-CPX-170560 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Son of sevenless homolog 1
Molecule details ›
Chains: A, B
Length: 852 amino acids
Theoretical weight: 99.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains:
Structure domains:
Length: 852 amino acids
Theoretical weight: 99.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q07889 (Residues: 198-1049; Coverage: 64%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ALS BEAMLINE 8.2.2
Spacegroup:
P212121
Expression system: Escherichia coli BL21
