Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149581 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Interleukin-10
Molecule details ›
Chain: L
Length: 160 amino acids
Theoretical weight: 18.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Interleukin 10
Structure domains: Growth Hormone; Chain: A;
Length: 160 amino acids
Theoretical weight: 18.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P22301 (Residues: 19-178; Coverage: 100%)
Sequence domains: Interleukin 10
Structure domains: Growth Hormone; Chain: A;
Interleukin-10 receptor subunit alpha
Molecule details ›
Chain: R
Length: 214 amino acids
Theoretical weight: 24.51 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Sequence domains: Tissue factor
Structure domains: Immunoglobulins
Length: 214 amino acids
Theoretical weight: 24.51 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical: Q13651 (Residues: 22-235; Coverage: 38%)
Sequence domains: Tissue factor
Structure domains: Immunoglobulins
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL9-2
Spacegroup:
P3212
Expression systems:
- Escherichia coli BL21(DE3)
- Drosophila melanogaster
