› 1y7x

Solution NMR

Solution structure of a two-repeat fragment of major vault protein

Released:
DOI: 10.2210/pdb1y7x/pdb
PDB entry 1y7x coloured by chain, ensemble of 20 models, front view.
PDB entry 1y7x coloured by chain, ensemble of 20 models, side view.
PDB entry 1y7x coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of a two-repeat fragment of major vault protein.
Kozlov G, Vavelyuk O, Minailiuc O, Banville D, Gehring K, Ekiel I
J Mol Biol 356 444-52 (2006)
PMID: 16373071

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172094 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major vault protein Chain: A
Molecule details ›
Chain: A
Length: 113 amino acids
Theoretical weight: 12.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q14764 (Residues: 113-221; Coverage: 12%)
Gene names: LRP, MVP
Sequence domains: Major Vault Protein repeat domain
Structure domains: Major Vault Protein repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

5 review citations

RNA packaging into extracellular vesicles: An orchestra of RNA-binding proteins?
Fabbiano et al. (2020)
4 more

2 mentions without citation

Draft crystal structure of the vault shell at 9-A resolution.
Anderson et al. (2007)
1 more