1ykb

X-ray diffraction
2.6Å resolution

Crystal Structure of Insect Cell Expressed IL-22

Released:
Source organism: Homo sapiens
Primary publication:
Structure of insect-cell-derived IL-22.
Acta Crystallogr D Biol Crystallogr 61 942-50 (2005)
PMID: 15983417

Function and Biology Details

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190460 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Interleukin-22 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 142 amino acids
Theoretical weight: 16.4 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9GZX6 (Residues: 38-179; Coverage: 97%)
Gene names: IL22, ILTIF, UNQ3099/PRO10096, ZCYTO18
Sequence domains: Interleukin 22 IL-10-related T-cell-derived-inducible factor
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, FUC, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 64.877Å b: 62.227Å c: 139.524Å
α: 90° β: 91.35° γ: 90°
R-values:
R R work R free
0.232 0.232 0.265
Expression system: Not provided