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Solution NMR

Solution structure of DNA binding domain A (DBD-A) of S.cerevisiae Replication Protein A (RPA)

Released:
DOI: 10.2210/pdb1ynx/pdb
PDB entry 1ynx coloured by chain, ensemble of 22 models, front view.
PDB entry 1ynx coloured by chain, ensemble of 22 models, side view.
PDB entry 1ynx coloured by chain, ensemble of 22 models, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Solution structure of the DNA-binding domain of RPA from Saccharomyces cerevisiae and its interaction with single-stranded DNA and SV40 T antigen.
Park CJ, Lee JH, Choi BS
Nucleic Acids Res 33 4172-81 (2005)
PMID: 16043636

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149595 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Replication factor A protein 1 Chain: A
Molecule details ›
Chain: A
Length: 114 amino acids
Theoretical weight: 13.27 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P22336 (Residues: 181-294; Coverage: 18%)
Gene names: BUF2, FUN3, RFA1, RPA1, YAR007C
Sequence domains: OB-fold nucleic acid binding domain
Structure domains: Nucleic acid-binding proteins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Torsional Angle Dynamics with Internal Variable Module
Expression system: Escherichia coli

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Citations

3 review citations

A dynamic model for replication protein A (RPA) function in DNA processing pathways.
Fanning et al. (2006)
2 more

3 mentions without citation

A structural and dynamic model for the assembly of Replication Protein A on single-stranded DNA.
Yates et al. (2018)
2 more