› 1yxr

Solution NMR

NMR Structure of VPS4A MIT Domain

Released:
DOI: 10.2210/pdb1yxr/pdb
PDB entry 1yxr coloured by chain, ensemble of 20 models, front view.
PDB entry 1yxr coloured by chain, ensemble of 20 models, side view.
PDB entry 1yxr coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Scott JA, Gaspar J, Stuchell M, Alam S, Skalicky J, Sundquist WI

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193986 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vacuolar protein sorting-associated protein 4A Chain: A
Molecule details ›
Chain: A
Length: 77 amino acids
Theoretical weight: 9.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9UN37 (Residues: 1-77; Coverage: 18%)
Gene names: VPS4, VPS4A
Sequence domains: MIT (microtubule interacting and transport) domain
Structure domains: Phosphotransferase system, lactose/cellobiose-type IIA subunit

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: automated NOE assignment using CYANA and torsion angle dynamics for structure calculations
Expression system: Escherichia coli BL21

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