1z7c

X-ray diffraction
2Å resolution

Crystal Structure of Human Placental Lactogen

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure and site 1 binding energetics of human placental lactogen.
J Mol Biol 358 773-84 (2006)
PMID: 16546209

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-143640 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chorionic somatomammotropin hormone 1 Chain: A
Molecule details ›
Chain: A
Length: 191 amino acids
Theoretical weight: 22.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P0DML2 (Residues: 27-217; Coverage: 100%)
Gene name: CSH1
Sequence domains: Somatotropin hormone family
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-D, APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 115.504Å b: 30.047Å c: 53.49Å
α: 90° β: 113.38° γ: 90°
R-values:
R R work R free
0.233 0.229 0.267
Expression system: Escherichia coli BL21