› 1z9m

X-ray diffraction
2.4Å resolution

Crystal Structure of Nectin-like molecule-1 protein Domain 1

Released:
DOI: 10.2210/pdb1z9m/pdb
PDB entry 1z9m coloured by chain, front view.
PDB entry 1z9m coloured by chain, side view.
PDB entry 1z9m coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the V domain of human Nectin-like molecule-1/Syncam3/Tsll1/Igsf4b, a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule.
Dong X, Xu F, Gong Y, Gao J, Lin P, Chen T, Peng Y, Qiang B, Yuan J, Peng X, Rao Z
J Biol Chem 281 10610-7 (2006)
PMID: 16467305

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185349 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cell adhesion molecule 3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 145 amino acids
Theoretical weight: 15.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q8N126 (Residues: 25-135; Coverage: 30%)
Gene names: CADM3, IGSF4B, NECL1, SYNCAM3, TSLL1, UNQ225/PRO258
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BSRF BEAMLINE 3W1A
Spacegroup: C2221
Unit cell:
a: 77.1Å b: 77.5Å c: 102.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.244 0.227 0.274
Expression system: Escherichia coli BL21

Quick links

Citations

8 review citations

Immunoglobulin superfamily cell adhesion molecules: zippers and signals.
Aricescu et al. (2007)
7 more

7 mentions without citation

Sequence, structure, function, immunity: structural genomics of costimulation.
Chattopadhyay et al. (2009)
6 more