› 1zk9

X-ray diffraction
2.18Å resolution

NF-kB RelB forms an intertwined homodimer

Released:
DOI: 10.2210/pdb1zk9/pdb
PDB entry 1zk9 coloured by chain, front view.
PDB entry 1zk9 coloured by chain, side view.
PDB entry 1zk9 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
NF-kappaB RelB forms an intertwined homodimer.
Huang DB, Vu D, Ghosh G
Structure 13 1365-73 (2005)
PMID: 16154093

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170085 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription factor RelB Chain: A
Molecule details ›
Chain: A
Length: 110 amino acids
Theoretical weight: 12.4 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q04863 (Residues: 276-378; Coverage: 19%)
Gene name: Relb
Sequence domains: Rel homology dimerisation domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P3121
Unit cell:
a: 69.2Å b: 69.2Å c: 64.74Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.195 0.195 0.218
Expression system: Escherichia coli BL21

Quick links

Citations

15 review citations

Circuitry of nuclear factor kappaB signaling.
Hoffmann et al. (2006)
14 more

4 mentions without citation

NF-κB regulation: lessons from structures.
Ghosh et al. (2012)
3 more