› 1zoo

X-ray diffraction
3Å resolution

CD11A I-DOMAIN WITH BOUND MAGNESIUM ION

Released:
DOI: 10.2210/pdb1zoo/pdb
PDB entry 1zoo coloured by chain, front view.
PDB entry 1zoo coloured by chain, side view.
PDB entry 1zoo coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin.
Qu A, Leahy DJ
Structure 4 931-42 (1996)
PMID: 8805579

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149037 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrin alpha-L Chains: A, B
Molecule details ›
Chains: A, B
Length: 187 amino acids
Theoretical weight: 21.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P20701 (Residues: 150-336; Coverage: 16%)
Gene names: CD11A, ITGAL
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain

Ligands and Environments

2 bound ligands:
Ligand MG 2 x MG
Ligand CL 2 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21212
Unit cell:
a: 75.56Å b: 78.32Å c: 66.28Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.279 0.279 0.264
Expression system: Escherichia coli

Quick links

Citations

23 review citations

Integrins: bidirectional, allosteric signaling machines.
Hynes RO. (2002)
22 more

9 mentions without citation

Rolling cell adhesion.
McEver et al. (2010)
8 more