› 1zsx

X-ray diffraction
1.9Å resolution

Crystal Structure Of Human Potassium Channel Kv Beta-subunit (KCNAB2)

Released:
DOI: 10.2210/pdb1zsx/pdb
PDB entry 1zsx coloured by chain, front view.
PDB entry 1zsx coloured by chain, side view.
PDB entry 1zsx coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Wennerstrand P, Johannsson I, Ugochukwu E, Kavanagh K, Edwards A, Arrowsmith C, Williams L, Sundstrom M, Guo K, von Delft F, Oppermann U, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo tetramer (preferred)
homo octamer
Assembly name:
PDBe Complex ID:
PDB-CPX-171632 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Voltage-gated potassium channel subunit beta-2 Chain: A
Molecule details ›
Chain: A
Length: 347 amino acids
Theoretical weight: 38.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13303 (Residues: 39-360; Coverage: 88%)
Gene names: KCNA2B, KCNAB2, KCNK2
Sequence domains: Aldo/keto reductase family
Structure domains: NADP-dependent oxidoreductase domain

Ligands and Environments

2 bound ligands:
Ligand CL 4 x CL
Ligand NAP 1 x NAP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: I422
Unit cell:
a: 113.231Å b: 113.231Å c: 142.505Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.146 0.145 0.172
Expression system: Escherichia coli BL21(DE3)

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