1zvs

X-ray diffraction
2.8Å resolution

Crystal structure of the first class MHC mamu and Tat-Tl8 complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-158315 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
MHC class I antigen Chains: A, D
Molecule details ›
Chains: A, D
Length: 278 amino acids
Theoretical weight: 32.14 KDa
Source organism: Macaca mulatta
Expression system: Escherichia coli
Structure domains:
Beta-2-microglobulin Chains: B, E
Molecule details ›
Chains: B, E
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Tat-Tl8 Chains: C, F
Molecule details ›
Chains: C, F
Length: 8 amino acids
Theoretical weight: 832 Da

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: I422
Unit cell:
a: 182.142Å b: 182.142Å c: 156.693Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.217 0.257
Expression system: Escherichia coli