› 1a06

X-ray diffraction
2.5Å resolution

CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT

Released:
DOI: 10.2210/pdb1a06/pdb
PDB entry 1a06 coloured by chain, front view.
PDB entry 1a06 coloured by chain, side view.
PDB entry 1a06 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Structural basis for the autoinhibition of calcium/calmodulin-dependent protein kinase I.
Goldberg J, Nairn AC, Kuriyan J
Cell 84 875-87 (1996)
PMID: 8601311

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179016 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent protein kinase type 1 Chain: A
Molecule details ›
Chain: A
Length: 332 amino acids
Theoretical weight: 37.52 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: Q63450 (Residues: 1-333; Coverage: 89%)
Gene name: Camk1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: I222
Unit cell:
a: 65.2Å b: 76Å c: 148.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.201 0.313
Expression system: Not provided

Quick links

Citations

44 review citations

The conformational plasticity of protein kinases.
Huse et al. (2002)
43 more

35 mentions without citation

Ca(2+)/calmodulin-dependent protein kinases.
Swulius et al. (2008)
34 more