› 1ac6

X-ray diffraction
2.3Å resolution

CRYSTAL STRUCTURE OF A VARIABLE DOMAIN MUTANT OF A T-CELL RECEPTOR ALPHA CHAIN

Released:
DOI: 10.2210/pdb1ac6/pdb
PDB entry 1ac6 coloured by chain, front view.
PDB entry 1ac6 coloured by chain, side view.
PDB entry 1ac6 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Dual conformations of a T cell receptor V alpha homodimer: implications for variability in V alpha V beta domain association.
Li H, Lebedeva MI, Ward ES, Mariuzza RA
J Mol Biol 269 385-94 (1997)
PMID: 9199407

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177774 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ig-like domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 110 amino acids
Theoretical weight: 12.1 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q5R1F5 (Residues: 21-112; Coverage: 100%)
Gene name: TRAV6D-7
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P212121
Unit cell:
a: 72.43Å b: 64.82Å c: 45.54Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.161 0.161 0.279

Quick links

Citations

6 review citations

How TCRs bind MHCs, peptides, and coreceptors.
Rudolph et al. (2006)
5 more

1 mention without citation

Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins.
Pechmann et al. (2009)