› 1aii

X-ray diffraction
1.95Å resolution

ANNEXIN III

Released:
DOI: 10.2210/pdb1aii/pdb
PDB entry 1aii coloured by chain, front view.
PDB entry 1aii coloured by chain, side view.
PDB entry 1aii coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Can enzymatic activity, or otherwise, be inferred from structural studies of annexin III?
Perron B, Lewit-Bentley A, Geny B, Russo-Marie F
J Biol Chem 272 11321-6 (1997)
PMID: 9111038

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146163 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Annexin A3 Chain: A
Molecule details ›
Chain: A
Length: 323 amino acids
Theoretical weight: 36.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P12429 (Residues: 1-323; Coverage: 100%)
Gene names: ANX3, ANXA3
Sequence domains: Annexin
Structure domains: Annexin

Ligands and Environments

3 bound ligands:
Ligand CA 5 x CA
Ligand SO4 1 x SO4
Ligand ETA 1 x ETA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LURE BEAMLINE D41A
Spacegroup: P21
Unit cell:
a: 42.29Å b: 68.72Å c: 50.59Å
α: 90° β: 94.27° γ: 90°
R-values:
R R work R free
0.196 0.193 0.237
Expression system: Escherichia coli

Quick links

Citations

3 review citations

The role of annexin A3 playing in cancers.
Wu et al. (2013)
2 more

33 mentions without citation

Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme.
White et al. (2008)
32 more