› 1aml

Solution NMR

THE ALZHEIMER`S DISEASE AMYLOID A4 PEPTIDE (RESIDUES 1-40)

Released:
DOI: 10.2210/pdb1aml/pdb
PDB entry 1aml coloured by chain, ensemble of 20 models, front view.
PDB entry 1aml coloured by chain, ensemble of 20 models, side view.
PDB entry 1aml coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease.
Sticht H, Bayer P, Willbold D, Dames S, Hilbich C, Beyreuther K, Frank RW, Rösch P
Eur J Biochem 233 293-8 (1995)
PMID: 7588758

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138353 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Amyloid-beta protein 40 Chain: A
Molecule details ›
Chain: A
Length: 40 amino acids
Theoretical weight: 4.34 KDa
Source organism: Homo sapiens
Expression system: unidentified
UniProt:
  • Canonical: P05067 (Residues: 672-711; Coverage: 5%)
Gene names: A4, AD1, APP
Sequence domains: Beta-amyloid peptide (beta-APP)
Structure domains: Amyloidogenic glycoprotein, amyloid-beta peptide

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: unidentified

Quick links

Citations

23 review citations

Alzheimer's amyloid fibrils: structure and assembly.
Serpell LC. (2000)
22 more

24 mentions without citation

The amyloid-beta precursor protein: integrating structure with biological function.
Reinhard et al. (2005)
23 more