› 1amt

X-ray diffraction
1.5Å resolution

Crystal structure of alamethicin at 1.5 angstrom resolution

Released:
DOI: 10.2210/pdb1amt/pdb
PDB entry 1amt coloured by chain, front view.
PDB entry 1amt coloured by chain, side view.
PDB entry 1amt coloured by chain, top view.
Source organism: Trichoderma viride
Primary publication:
A voltage-gated ion channel model inferred from the crystal structure of alamethicin at 1.5-A resolution.
Fox RO, Richards FM
Nature 300 325-30 (1982)
PMID: 6292726

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162105 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ALAMETHICIN F30 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 21 amino acids
Theoretical weight: 1.95 KDa
Source organism: Trichoderma viride
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand CCN 2 x CCN
Ligand MOH 13 x MOH
2 modified residues:
Ligand AIB 24 x AIB
Ligand PHL 3 x PHL

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 33.33Å b: 29.62Å c: 23.2Å
α: 90° β: 120.4° γ: 90°
R-values:
R R work R free
0.155 not available not available
Expression system: Not provided

Quick links

Citations

47 review citations

Molecular basis of mechanotransduction in living cells.
Hamill et al. (2001)
46 more

19 mentions without citation

Helix insertion into bilayers and the evolution of membrane proteins.
Renthal R. (2010)
18 more