› › Function and Biology

HUMAN ARYLSULFATASE A

Source organism: Homo sapiens
Biochemical function: metal ion binding
Biological process: lipid metabolic process
Cellular component: extracellular exosome

Quick links

EC 3.1.6.8: Cerebroside-sulfatase

Reaction catalysed:
A cerebroside 3-sulfate + H(2)O = a cerebroside + sulfate
Systematic name:
Cerebroside-3-sulfate 3-sulfohydrolase
Alternative Name(s):
  • Arylsulfatase A
  • Cerebroside sulfate sulfatase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF14707
Domain description: C-terminal region of aryl-sulfatase
Occurring in:
  1. Arylsulfatase A
The deposited structure of PDB entry 1auk contains 1 copy of Pfam domain PF14707 (C-terminal region of aryl-sulfatase) in Arylsulfatase A. Showing 1 copy in chain A.

PF00884
Domain description: Sulfatase
Occurring in:
  1. Arylsulfatase A
The deposited structure of PDB entry 1auk contains 1 copy of Pfam domain PF00884 (Sulfatase) in Arylsulfatase A. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR017850
Domain description: Alkaline-phosphatase-like, core domain superfamily
Occurring in:
  1. Arylsulfatase A
IPR024607
Domain description: Sulfatase, conserved site
Occurring in:
  1. Arylsulfatase A
IPR000917
Domain description: Sulfatase, N-terminal
Occurring in:
  1. Arylsulfatase A

Structure domains

CATH CATH domains
3.40.720.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Alkaline Phosphatase, subunit A
Homology: Alkaline Phosphatase, subunit A
Occurring in:
  1. Arylsulfatase A
The deposited structure of PDB entry 1auk contains 1 copy of CATH domain 3.40.720.10 (Alkaline Phosphatase, subunit A) in Arylsulfatase A. Showing 1 copy in chain A.
3.30.1120.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Arylsulfatase, C-terminal domain
Homology: Arylsulfatase, C-terminal domain
Occurring in:
  1. Arylsulfatase A
The deposited structure of PDB entry 1auk contains 1 copy of CATH domain 3.30.1120.10 (Arylsulfatase, C-terminal domain) in Arylsulfatase A. Showing 1 copy in chain A.
SCOP SCOP annotation
53653
Class: Alpha and beta proteins (a/b)
Fold: Alkaline phosphatase-like
Superfamily: Alkaline phosphatase-like
Occurring in:
  1. Arylsulfatase A
The deposited structure of PDB entry 1auk contains 1 copy of SCOP domain 53653 (Arylsulfatase) in Arylsulfatase A. Showing 1 copy in chain A.

Quick links