› 1axn

X-ray diffraction
1.78Å resolution

THE HIGH RESOLUTION STRUCTURE OF ANNEXIN III SHOWS DIFFERENCES WITH ANNEXIN V

Released:
DOI: 10.2210/pdb1axn/pdb
PDB entry 1axn coloured by chain, front view.
PDB entry 1axn coloured by chain, side view.
PDB entry 1axn coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The high-resolution crystal structure of human annexin III shows subtle differences with annexin V.
Favier-Perron B, Lewit-Bentley A, Russo-Marie F
Biochemistry 35 1740-4 (1996)
PMID: 8639653

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146163 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Annexin A3 Chain: A
Molecule details ›
Chain: A
Length: 323 amino acids
Theoretical weight: 36.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P12429 (Residues: 2-323; Coverage: 100%)
Gene names: ANX3, ANXA3
Sequence domains: Annexin
Structure domains: Annexin

Ligands and Environments

1 bound ligand:
Ligand CA 5 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LURE BEAMLINE DW32
Spacegroup: P21
Unit cell:
a: 42.544Å b: 69.085Å c: 50.95Å
α: 90° β: 95.55° γ: 90°
R-values:
R R work R free
0.177 not available 0.221
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Annexins and membrane dynamics.
Gerke et al. (1997)
6 more

22 mentions without citation

Zooming into the Dark Side of Human Annexin-S100 Complexes: Dynamic Alliance of Flexible Partners.
Weisz et al. (2020)
21 more