› 1b6u

X-ray diffraction
3Å resolution

CRYSTAL STRUCTURE OF THE HUMAN KILLER CELL INHIBITORY RECEPTOR (KIR2DL3) SPECIFIC FOR HLA-CW3 RELATED ALLELES

Released:
DOI: 10.2210/pdb1b6u/pdb
PDB entry 1b6u coloured by chain, front view.
PDB entry 1b6u coloured by chain, side view.
PDB entry 1b6u coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the human p58 killer cell inhibitory receptor (KIR2DL3) specific for HLA-Cw3-related MHC class I.
Maenaka K, Juji T, Stuart DI, Jones EY
Structure 7 391-8 (1999)
PMID: 10196125

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155113 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Killer cell immunoglobulin-like receptor 2DL3 Chain: A
Molecule details ›
Chain: A
Length: 257 amino acids
Theoretical weight: 28.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P43628 (Residues: 22-245; Coverage: 70%)
Gene names: CD158B2, KIR2DL3, KIRCL23, NKAT2
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6A
Spacegroup: P6522
Unit cell:
a: 95.4Å b: 95.4Å c: 130.8Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.248 0.248 0.32
Expression system: Escherichia coli

Quick links

Citations

21 review citations

KIR: diverse, rapidly evolving receptors of innate and adaptive immunity.
Vilches et al. (2002)
20 more

10 mentions without citation

The structural basis of ligand recognition by natural killer cell receptors.
Joyce et al. (2011)
9 more