Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- SH2 domain
- SH2 domain superfamily
- STAT1, SH2 domain
- STAT transcription factor, DNA-binding
- STAT transcription factor, DNA-binding, N-terminal
- p53-like transcription factor, DNA-binding domain superfamily
- STAT transcription factor, all-alpha domain
- STAT transcription factor, coiled coil
1 more domain
Structure domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
STAT1 homodimer and DNA (preferred)
PDBe Complex ID:
PDB-CPX-218897 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (3 distinct):
Signal transducer and activator of transcription 1-alpha/beta
Molecule details ›
Chain: A
Length: 575 amino acids
Theoretical weight: 66.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 575 amino acids
Theoretical weight: 66.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P42224 (Residues: 136-710; Coverage: 77%)
Sequence domains:
- STAT protein, all-alpha domain
- STAT protein, DNA binding domain
- Signal transducer and activator of transcription, linker domain
- SH2 domain
